![]() 2, 5, 8, 9Ī twenty-six-year-old female presented to our clinic on with a painful right eye which was swollen shut. 5, 6, 11, 13, 14, 17–19 While most corneal ulcers in North America are bacterial in origin (accounting for approximately 90% of cases of microbial keratitis) and are most often caused by contact lens wear, trauma (often fungal) is the leading cause of ulcers in developing countries. 3 The most common pathogens implicated are staphylococci and pseudomonas. ![]() 9 Microbial keratitis increased in prevalence following the introduction of soft lenses in the 1970s. 10 Bacterial infection accounts for approximately 90% of microbial keratitis. ![]() 12, 14, 15 Corneal ulcers generally occur when the normal eye's natural resistance to infection has been compromised from either trauma or contact lens wear. ![]() 10, 15, 16Ī corneal ulcer is defined by a corneal infiltrate associated with an overlying epithelial defect. 4, 8, 9 Estimates put the number affected annually by bacterial keratitis in the U.S. 10, 13Ĭontact lens (CL) wear is the main risk factor, 3, 6, 14, 15 and sleeping in contact lenses is the major risk factor among contact lens wearers. 1–12 Either untreated or severe bacterial keratitis may result in perforation and endophthalmitis. Bacterial keratitis (corneal ulcer) is a sight-threatening contact lens complication.
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